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Possible cause for some cases of asthma discovered
Possible cause for some cases of asthma discovered (April 28, 2015 - Insidermedicine)
From the UK - A new report published in Science Translational Medicine identifies a potential root cause and novel treatment for some cases of asthma. Researchers studied a mouse model and used human airway tissue from both asthmatic and non-asthmatic people. They found that airway inflammation, caused by triggers such as allergens, cigarette smoke and car fumes,  releases chemicals that activate the calcium sensing receptors (CaSR) in an individual’s airway. This in turn causes airway twitchiness, inflammation and narrowing. Researchers made use of a compound known as a calcilytic, which was nebulized directly into the lungs. They found that this drug deactivated the receptor and prevented all of these symptoms.