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Obesity raises risk of colon cancer, while physical activity lowers risk
Obesity raises risk of colon cancer, while physical activity lowers risk

(February 26, 2013 - Insidermedicine)

From Boston – According to a new report published in Cancer Research, obesity raises risk of a subtype of colon cancer while physical activity lowers risk. Researchers studied data on over 100,000 women and 45,000 men taking part in two long term studies. Nearly 2,300 people developed colorectal cancer over the study period, 860 of whom had a biomarker CTNNB1 that is indicative of a subtype of colon cancer. Results showed that every 5 kg/m2 of BMI raised risk of CTNNB1-negative cancer by 34%, but had no association with CTNNB1-positive cancer. Increasing physical activity, in contrast, was found to significantly reduce risk of CTNNB1-negative cancer, while also having no effect on CTNNB1-positive cancer.

 
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