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Gene found in eye melanoma associated with good prognosis
Gene found in eye melanoma associated with good prognosis

(January 24, 2013 - Insidermedicine)

From St. Louis - A genetic mutation found in eye melanomas is linked to a good prognosis, according to a report published in Nature Genetics. Researchers studied 18 uveal melanoma patients, 11 of whom carried a genetic mutation known to have a bad prognosis and 7 who did not have the mutation. Scientists discovered a new mutation in the SF3B1 gene in three of these patients. They then examined uveal melanomas in 102 additional patients and found the new mutation in nearly 20% of tumours. This mutation was linked to favourable features, such as younger age and a lower metastasis rate, and occurred in tumours much less likely to become deadly.

 
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