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Cholesterol linked to macular degeneration
Cholesterol linked to macular degeneration

(April 2, 2013 - Insidermedicine)

From St. Louis - A new report published in Cell Metabolism finds that cholesterol buildup that occurs during atherosclerosis may also cause macular degeneration. Researchers studied mice, examining the rodents 'macrophages' as they aged. Macrophages are immune cells that are responsible for removing cholesterol and fats from tissues in the body. As people age, cholesterol builds up and the macrophages malfunction, an aspect that can result in atherosclerosis and new blood vessel growth found in macular degeneration. Researchers found that the macrophages in old mice had low levels of a protein, known as ABCA1, that removes cholesterol from cells. When researchers gave the rodents a medication that restored levels of ABCA1, cholesterol was removed more effectively--and the development of new blood vessels was slowed.

 
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