(January 22, 2008 - Insidermedicine) From California - Caffeine may raise the risk of miscarriage. In a study of over 1,000 pregnant women, those who consumed 200 mg or more of caffeine, the equivalent of 10 oz of coffee or 25 oz of tea, were twice as likely to have a miscarriage. While these results conflict with those from other studies, pregnant women should consider limiting their caffeine intake.

From Minnesota - Genetic variations can predict who might better respond to certain blood pressure lowering medications. In an evaluation of nearly 40,000 patients, genetic variability in the NPPA gene predicted better response to some pressure lowering medications. The findings, and pharmacogenetics in general, could one day help to determine how medicines will be prescribed to maximize efficacy and lower adverse events.

And finally, from Italy - A new study suggests that low levels of vitamin E are associated with declines in physical function in the elderly. In a study of nearly 700 adults 65 years of age or older, those with low levels of vitamin E at the start of the study were the most likely to experience a physical decline during the 3-year study period. Low levels of vitamin E have been linked to increased oxidative stress, atherosclerosis and neurodegenerative disorders.

For Insidermedicine in 60, I'm Dr. Susan Sharma.